About ACTOS

Special offers

ACTOS Advantage® Program
Together Rx Access® Program
Patient Assistance Program

ACTOS Advantage® Program

If eating right and staying active aren’t enough to help you control your blood sugar, ask your doctor about ACTOS. Whether you are new to ACTOS or the ACTOS Family Products (ACTOplus met or duetact) or have been taking it for some time, you may be eligible to save up to $50 on your prescription for an ACTOS Family Product with the ACTOS Advantage® Program.*

To get your prescription rebate for an ACTOS Family Product, here's what you need to do...

  • Fill your prescription for an ACTOS Family Product.
  • Check Eligibility Requirements and Terms and Conditions on this page.
  • If you are eligible, print your name, address, and the amount paid on the back of the rebate.
  • Sign and date the rebate (required) and mail with your original receipt to the address below:

          Takeda Pharmaceuticals America, Inc.
          PO Box 2062
          Morrisville, PA 19067-0562


Click on rebate offer to print.
*This offer is not valid for all patients. You must meet eligibility requirements. See Terms & Conditions for restrictions.

Eligibility Requirements

This rebate cannot be used if any part of your prescription is covered by: (i) any federal or state healthcare program (Medicare, Medicaid, VA, TriCARE, etc.), including a state medical or pharmaceutical assistance program, (ii) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, (iii) insurance that is paying the entire cost of the prescription, or (iv) an insurer or other Third Party Payor in Massachusetts.

Terms & Conditions

You must meet Eligibility Requirements. You agree to report your use of this rebate to any Third Party that reimburses you or pays for any part of the prescription price. You additionally agree that you will not submit the cost of any portion of the product dispensed pursuant to this rebate to a federal or state healthcare program for purposes of counting it toward your out-of-pocket expenses (such as TrOOP under Medicare Part D). The amount of this rebate is not to exceed $50 or your co-pay amount, whichever is less. This rebate is not valid with any other program, discount, or incentive involving an ACTOS Family Product. Offer is invalid for submissions postmarked later than 56 days from the dispense date on the original receipt. This offer may be rescinded, revoked, or amended without notice. No reproductions. This rebate is void where prohibited by law, taxed, or restricted. Limit one rebate per purchase. Cash value of 1/100 of 1¢. For questions about this rebate, call the Customer Service Center at (888) 838-9866.

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Save on prescriptions with the Together Rx Access® Program‡

  • Together Rx Access® is a prescription savings program that offers a free, easy way to save on prescription medications. Most cardholders save 25% to 40% on brand-name medicines and also save on a wide range of generic medications.§
  • To learn more about how to apply, eligibility requirements, and other information about the program, call 1-800-444-4106 or visit TogetherRxAccess.com.

Together Rx Access

‡Eligibility requirements include household income, not being eligible for Medicare, not having prescription drug coverage (public or private), and being a legal resident of the United States or Puerto Rico. For more information regarding eligibility, contact Together Rx Access at 1-800-444-4106.

§Each cardholder’s savings depend on such factors as the particular drug purchased, amount purchased, and pharmacy where purchased. Participating companies independently set the level of savings offered and the products included in the program. Those decisions are subject to change.

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Patient Assistance Program

  • The Patient Assistance Program gives patients who would otherwise find it financially difficult to receive type 2 diabetes treatment access to free ACTOS therapy.
    • You must meet the required income level, not have medical insurance coverage for prescriptions and/or be ineligible for government or private programs, and must be a legal resident of the United States.
    • If you have Medicare Part D coverage, you may also be eligible to receive assistance.
  • For information on how to enroll, call 1-800-830-9159.
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Indications and Usage
ACTOS is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes.

ACTOplus met is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes.

Duetact is a prescription medication used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes.

ACTOS, ACTOplus met, and duetact are not for patients with type 1 “juvenile” diabetes or diabetic ketoacidosis.

ACTOS, ACTOplus met, and duetact have not been studied in children and are not recommended for children under the age of 18.

Important Safety Information
ACTOS, ACTOplus met, and duetact are not for everyone. Certain patients with heart failure should not start taking ACTOS, ACTOplus met, or duetact. ACTOS, ACTOplus met, and duetact can cause new, or worsen, heart failure. Talk to your doctor immediately if you experience unusually fast weight gain, fluid retention (swelling), shortness of breath, unusual tiredness, or slow heartbeat.

Warnings Specific to ACTOplus met
Metformin, one of the medicines in ACTOplus met, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital.

Because lactic acidosis occurs most frequently in people with kidney problems, ACTOplus met should not be used in people with kidney disease or in people 80 years of age or older whose kidneys do not work properly.

ACTOplus met should not be taken by people with metabolic acidosis.

ACTOplus met should not be taken by people who drink excessive amounts of alcohol.

Talk to your doctor if you are going to have an X-ray procedure using injectable dye and are taking ACTOplus met.

Warning Specific to duetact
The chance of death from serious heart or blood vessel problems may be higher when using a sulfonylurea, an ingredient in duetact.

Taking glimepiride along with having an inherited condition where you don’t produce enough of the enzyme G6PD (G6PD deficiency) can cause hemolytic anemia, which causes your red blood cells to be destroyed too quickly.

Do not take ACTOS, ACTOplus met, or duetact if you have active liver disease. Your doctor should perform a blood test to check for liver problems before you start ACTOS, ACTOplus met, or duetact and periodically thereafter. Talk to your doctor immediately if you experience nausea, vomiting, stomach pain, unusual tiredness, loss of appetite, dark urine, or yellowing of the skin or eyes.

If you are of childbearing age, talk to your doctor before taking ACTOS, ACTOplus met, or duetact, as this could increase your chance of becoming pregnant. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

Some people taking ACTOS, ACTOplus met, or duetact may experience flulike symptoms, mild-to-moderate swelling of legs and ankles, anemia, and weight gain.

ACTOS may cause low blood sugar when taken in combination with insulin or sulfonylureas. Lightheadedness, shakiness, dizziness, or hunger may mean that your blood sugar is too low. Talk to your doctor if low blood sugar is a problem for you.

Patients with diabetes should have regular eye exams. If you experience vision problems, consult your doctor immediately. Some patients have experienced visual changes while taking ACTOS, ACTOplus met, or duetact.

Some people, particularly women, are at higher risk of having bone fractures while taking pioglitazone.

Other side effects of ACTOS may include cold-like symptoms, headache, sinus infection, muscle pain, tooth disorder, and sore throat.

Other side effects of ACTOplus met may include cold-like symptoms, diarrhea, nausea, headache, urinary tract infection, dizziness, sinus infection, and anemia.

Other side effects of duetact may include cold-like symptoms, headache, urinary tract infection, diarrhea, nausea, and limb pain.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch, or call 1-800-FDA-1088.

Please see ACTOS Complete Prescribing Information, including boxed warning and Medication Guide.
Please see ACTOplus met Complete Prescribing Information, including boxed warnings and Medication Guide.
Please see duetact Complete Prescribing Information, including boxed warning and Medication Guide.
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This site is intended for use by U.S. residents only.
ACTOS®, ACTOplus met®, and duetact® are registered trademarks of Takeda Pharmaceutical Company Limited
and are used under license by Takeda Pharmaceuticals America, Inc.