Special Savings Offers

Takeda Diabetes Savings Now Program
Save up to $60 on your next ACTOS prescription. Find out if you are eligible!

Together Rx Access® Program
Save 25%–40% on brand-name and generic medications

Patient Assistance Program
Gives patients who would otherwise find it financially difficult to receive treatment access to free ACTOS therapy

Takeda Diabetes Savings Now Program

With Takeda Diabetes Savings Now, eligible patients can get up to $60 instant savings on each prescription for up to 9 months on ACTOS, ACTOplus met, ACTOplus met XR, or duetact.†

Enjoy your savings with more convenience

  • You pay the first $20 of your co-pay and get up to $60 off any remaining out-of-pocket expense
  • You receive your savings immediately when you purchase your prescription

Click here to sign up today and find out if you are eligible to receive money-saving discounts!

†Must meet eligibility requirements.

Eligibility Requirements: This offer cannot be used if any part of your prescription is covered by: (i) any federal or state healthcare program (Medicare, Medicaid, VA, TriCARE, etc.), including a state medical or pharmaceutical assistance program, (ii) the Medicare Prescription Drug Program (Part D), or if you are currently in the coverage gap, (iii) insurance that is paying the entire cost of the prescription, or (iv) an insurer or other Third Party Payor in Massachusetts.

Terms & Conditions: You must meet Eligibility Requirements. You agree to report your use of this card to any Third Party that reimburses you or pays for any part of the prescription price. You additionally agree that you will not submit the cost of any portion of the product dispensed pursuant to this card to a federal or state healthcare program for purposes of counting it toward your out-of-pocket expenses (such as TrOOP under Medicare Part D). The amount of this card/offer is not to exceed $60 or your co-pay amount, whichever is less after you pay $20. This offer may be rescinded, revoked, or amended without notice. No reproductions. This card is void where prohibited by law, taxed, or restricted. Limit one offer per prescription or refill. Cash value of 1/100 of 1¢. For questions about this card, call The Customer Service Center at 1-888-838-9866.

Together Rx Access® Program

Save on prescriptions with the Together Rx Access® Program‡

  • Together Rx Access® is a prescription savings program that offers a free, easy way to save on prescription medications. Most cardholders save 25%–40% on brand-name medicines and also save on a wide range of generic medications.§
  • To learn more about how to apply, eligibility requirements, and other information about the program, call 1-800-444-4106 or visit TogetherRxAccess.com.

‡Eligibility requirements include household income, not being eligible for Medicare, not having prescription drug coverage (public or private), and being a legal resident of the United States or Puerto Rico. For more information regarding eligibility, contact Together Rx Access® at 1-800-444-4106.

§Each cardholder's savings depend on such factors as the particular drug purchased, amount purchased, and pharmacy where purchased. Participating companies independently set the level of savings offered and the products included in the program. Those decisions are subject to change.

Patient Assistance Program

  • The Patient Assistance Program gives patients who would otherwise find it financially difficult to receive type 2 diabetes treatment access to free ACTOS therapy.
    • You must meet the required income level, not have medical insurance coverage for prescriptions and/or be ineligible for government or private programs, and must be a legal resident of the United States.
    • If you have Medicare Part D coverage, you may also be eligible to receive assistance.
  • For information on how to enroll, call 1-800-830-9159.

Indications and Usage

ACTOS, ACTOplus met, ACTOplus met XR, and duetact are prescription medications used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. They are not for patients with type 1 "juvenile" diabetes or diabetic ketoacidosis.

Important Safety Information

Warning: Heart Failure

ACTOS, ACTOplus met, ACTOplus met XR, and duetact are not for everyone. These medications can cause or worsen heart failure. Heart failure means your heart does not pump blood well enough. Talk to your doctor immediately if you experience unusually fast weight gain, fluid retention (swelling), shortness of breath, or unusual tiredness. Certain patients with symptoms of heart failure should not start taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact. Do not take these medications if you have severe heart failure.

Warning: Lactic Acidosis Specific to ACTOplus met and ACTOplus met XR

Metformin, one of the medicines in ACTOplus met and ACTOplus met XR, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital. Because lactic acidosis occurs most frequently in people with kidney problems, ACTOplus met and ACTOplus met XR should not be used in people with kidney disease or in people 80 years of age or older whose kidneys do not work properly. ACTOplus met and ACTOplus met XR should not be taken by people with metabolic acidosis or who drink excessive amounts of alcohol.

Talk to your doctor if you are going to have an X-ray procedure using injectable dye and are taking ACTOplus met and ACTOplus met XR.

Do not take ACTOS, ACTOplus met, ACTOplus met XR, or duetact if you are allergic to any of their ingredients.

Warning Specific to duetact: The chance of death from serious heart or blood vessel problems may be higher when using a sulfonylurea, an ingredient in duetact.

ACTOS, ACTOplus met, ACTOplus met XR, and duetact may cause liver problems. Talk to your doctor immediately if you experience unexplained nausea, vomiting, stomach pain, unusual tiredness, loss of appetite, dark urine, or yellowing of the skin or eyes as these could be symptoms of liver damage.

Women are at higher risk of having broken bones (fractures) while taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact.

There may be an increased chance of having bladder cancer when you take ACTOS, ACTOplus met, ACTOplus met XR, or duetact. You should not take these medications if you are receiving treatment for bladder cancer. Tell your doctor right away if you have blood or a red color in your urine, have an increased need to urinate, or have pain while you urinate as these may be symptoms of bladder cancer.

Hypoglycemia may occur when taking anti-diabetic medications. Lightheadedness, shakiness, dizziness, or hunger may mean that your blood sugar is too low. Talk to your doctor if low blood sugar is a problem for you.

Some patients have experienced visual changes while taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact. If you experience vision problems, consult your doctor immediately. Have your eyes checked regularly.

If you are of childbearing age, but do not have regular monthly periods, talk to your doctor before taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact, as they could increase your chance of becoming pregnant.

Precaution Specific to duetact: Taking glimepiride along with having an inherited condition where you don’t produce enough of the enzyme G6PD (G6PD deficiency) can cause hemolytic anemia, which causes red blood cells to be destroyed too quickly.

The most common side effects of these products include:

  • ACTOS: cold-like symptoms, headache, sinus infection, muscle pain, and sore throat
  • ACTOplus met and ACTOplus met XR: cold or flu-like symptoms, diarrhea, nausea, headache, urinary tract infection, dizziness, and sinus infection
  • duetact: cold or flu-like symptoms, headache, urinary tract infection, diarrhea, nausea, and limb pain

Tell your doctor about all the medicines, vitamins, and supplements you take. Some medicines can affect each other. You may need to have your doses of certain medicines changed.

It is not known if ACTOS, ACTOplus met, ACTOplus met XR, or duetact can harm an unborn or nursing baby. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see ACTOS Complete Prescribing Information, including warning about heart failure, and Medication Guide.

Please see ACTOplus met Complete Prescribing Information, including warnings about heart failure and lactic acidosis, and Medication Guide.

Please see ACTOplus met XR Complete Prescribing Information, including warnings about heart failure and lactic acidosis, and Medication Guide.

Please see duetact Complete Prescribing Information, including warning about heart failure, and Medication Guide.

Copyright ©1999, 2011 Takeda Pharmaceuticals North America, Inc.

This site is intended for use by U.S. residents only.
ACTOS, ACTOplus met, ACTOplus met XR, and duetact are trademarks of
Takeda Pharmaceutical Company Limited registered with the U.S. Patent and
Trademark Office and used under license by Takeda Pharmaceuticals America, Inc.

Important Safety Information

Warning: Heart Failure

ACTOS, ACTOplus met, ACTOplus met XR, and duetact are not for everyone. These medications can cause or worsen heart failure. Heart failure means your heart does not pump blood well enough. Talk to your doctor immediately if you experience unusually fast weight gain, fluid retention (swelling), shortness of breath, or unusual tiredness. Certain patients with symptoms of heart failure should not start taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact. Do not take these medications if you have severe heart failure.

Warning: Lactic Acidosis Specific to ACTOplus met and ACTOplus met XR

Metformin, one of the medicines in ACTOplus met and ACTOplus met XR, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital. Because lactic acidosis occurs most frequently in people with kidney problems, ACTOplus met and ACTOplus met XR should not be used in people with kidney disease or in people 80 years of age or older whose kidneys do not work properly. ACTOplus met and ACTOplus met XR should not be taken by people with metabolic acidosis or who drink excessive amounts of alcohol.

Talk to your doctor if you are going to have an X-ray procedure using injectable dye and are taking ACTOplus met and ACTOplus met XR.

Do not take ACTOS, ACTOplus met, ACTOplus met XR, or duetact if you are allergic to any of their ingredients.

Warning Specific to duetact: The chance of death from serious heart or blood vessel problems may be higher when using a sulfonylurea, an ingredient in duetact.

ACTOS, ACTOplus met, ACTOplus met XR, and duetact may cause liver problems. Talk to your doctor immediately if you experience unexplained nausea, vomiting, stomach pain, unusual tiredness, loss of appetite, dark urine, or yellowing of the skin or eyes as these could be symptoms of liver damage.

Women are at higher risk of having broken bones (fractures) while taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact.

There may be an increased chance of having bladder cancer when you take ACTOS, ACTOplus met, ACTOplus met XR, or duetact. You should not take these medications if you are receiving treatment for bladder cancer. Tell your doctor right away if you have blood or a red color in your urine, have an increased need to urinate, or have pain while you urinate as these may be symptoms of bladder cancer.

Hypoglycemia may occur when taking anti-diabetic medications. Lightheadedness, shakiness, dizziness, or hunger may mean that your blood sugar is too low. Talk to your doctor if low blood sugar is a problem for you.

Some patients have experienced visual changes while taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact. If you experience vision problems, consult your doctor immediately. Have your eyes checked regularly.

If you are of childbearing age, but do not have regular monthly periods, talk to your doctor before taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact, as they could increase your chance of becoming pregnant.

Precaution Specific to duetact: Taking glimepiride along with having an inherited condition where you don’t produce enough of the enzyme G6PD (G6PD deficiency) can cause hemolytic anemia, which causes red blood cells to be destroyed too quickly.

The most common side effects of these products include:

  • ACTOS: cold-like symptoms, headache, sinus infection, muscle pain, and sore throat
  • ACTOplus met and ACTOplus met XR: cold or flu-like symptoms, diarrhea, nausea, headache, urinary tract infection, dizziness, and sinus infection
  • duetact: cold or flu-like symptoms, headache, urinary tract infection, diarrhea, nausea, and limb pain

Tell your doctor about all the medicines, vitamins, and supplements you take. Some medicines can affect each other. You may need to have your doses of certain medicines changed.

It is not known if ACTOS, ACTOplus met, ACTOplus met XR, or duetact can harm an unborn or nursing baby. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see ACTOS Complete Prescribing Information, including warning about heart failure, and Medication Guide.

Please see ACTOplus met Complete Prescribing Information, including warnings about heart failure and lactic acidosis, and Medication Guide.

Please see ACTOplus met XR Complete Prescribing Information, including warnings about heart failure and lactic acidosis, and Medication Guide.

Please see duetact Complete Prescribing Information, including warning about heart failure, and Medication Guide.

Indications and Usage

ACTOS, ACTOplus met, ACTOplus met XR, and duetact are prescription medications used with diet and exercise to improve blood sugar (glucose) control in adults with type 2 diabetes. They are not for patients with type 1 "juvenile" diabetes or diabetic ketoacidosis.